CIA
From One Truth Prevails - The Definitive Case Closed/Detective Conan Wiki
Ethan Hondou
Ethan Hondou (本堂 イーサン) a deceased and a hard-boiled CIA agent. He is Hidemi and Eisuke's father, He was originally thought by Conan and friends to have been a member of the Black Organization, but it turned out he had infiltrated them for the purposes of destroying them. When he and his daughter put a plan in motion to place a new CIA agent within the organization (her), Ethan noticed that the syndicate had bugged Hidemi's clothes. To protect his daughter, Ethan was forced to injure Hidemi and kill himself - making it look like he had interrogated her and she had killed him. His seiyū is Rikiya Koyama.
Eisuke Hondou
Eisuke Hondou (本堂 瑛祐 Hondō Eisuke) is Rachel's new classmate and is very clumsy. At first, Conan suspects he works for the Black Organization because not only does he look a lot like Rena Mizunashi, but he uses the same lie-detecting skills as she did. Conan is the only one having second thoughts about Eisuke; the others think that he's just a smart misguided student. Eisuke becomes an increasingly suspicious character as he begins looking for his sister, who looks almost identical to Rena Mizunashi; however, Eisuke insists that it is not Rena. However, his lie is revealed when he tracks down Kir/Rena to the hospital where she is hidden by the FBI, where it is revealed that Kir/Rena is indeed Eisuke's sister, and an undercover CIA agent. It is also revealed that Eisuke is the son of a deceased CIA agent, Ethan Hondou. The FBI offers him protection, but he refuses it. Currently, he intends to move to America to join the CIA like his sister and father. In episode 464, Eisuke tries to dig for information on how Richard Moore figures out his cases, and Conan mentally notes that Eisuke may be a threat to his secret identity. This thought becomes reality when Eisuke later tricks him by telling Conan that he is in love with Ran, provoking Conan to reveal his identity. His seiyū is Junko Noda.
Hidemi Hondou
Hidemi Hondou (本堂 瑛海 Hondō Hidemi) is Eisuke Hondou's sister. She was originally introduced as a newscaster under the name Rena Mizunashi. Hidemi Hondou also serves as a member of the Black Organization under the codename Kir[1]. She is later knocked into a coma and detained by FBI agents after being involved in a traffic accident. It is revealed that her name is most likely an alias that refers to "007". She later wakes up and it is ultimately revealed that she is an undercover CIA agent, working as a double agent within the Black Organization, trying to bring them down. The FBI manage to trick the Black Organization to take her in again. To prove her loyalty, she was ordered to kill Shuichi Akai. Under heavy surveillance, she reports information to Jodie Starling. Her seiyū is Kotono Mitsuishi.